MDR1/ABCB1 Antibody (S02-6B2)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-20044

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-20044-100ul
NBP3-20044-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S02-6B2

Concentration

0.3 mg/ml

View all MDR1/ABCB1 Antibodies »

Product Summary for MDR1/ABCB1 Antibody (S02-6B2)

Immunogen

Recombinant protein of human MDR1/ABCB1 (Uniprot # P08183)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MDR1/ABCB1 Antibody (S02-6B2)

Western Blot: MDR1/ABCB1 Antibody (S02-6B2) [NBP3-20044]

Western Blot: MDR1/ABCB1 Antibody (S02-6B2) [NBP3-20044]

Western Blot: MDR1/ABCB1 Antibody (S02-6B2) [NBP3-20044] - Western blot detection of MDR1/ABCB1 in Hela cell lysates using NBP3-20044 (1:1000 diluted). Predicted band size: 142kDa. Observed band size: 130-180kDa.

Applications for MDR1/ABCB1 Antibody (S02-6B2)

Application
Recommended Usage

Western Blot

1/1000-1/2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MDR1/ABCB1

MDR1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). MDR1 is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. (provided by RefSeq)

Long Name

ATP-binding Cassette, Sub-family B (MDR/TAP), Member 1B

Alternate Names

ABC20, ABCB1, ABCB1B, CD243, CLCS, GP170, IBD13, PGY1

Gene Symbol

ABCB1

Additional MDR1/ABCB1 Products

Product Documents for MDR1/ABCB1 Antibody (S02-6B2)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MDR1/ABCB1 Antibody (S02-6B2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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