MEKK2 Antibody (SR3035)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27740

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-27740-100ul
NBP3-27740-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR3035

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MEKK2 Antibodies »

Product Summary for MEKK2 Antibody (SR3035)

Immunogen

A synthesized peptide derived from human MEKK2 (Uniprot #: Q9Y2U5)

Specificity

Detects endogenous levels of MEKK2

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

70 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for MEKK2 Antibody (SR3035)

Western Blot: MEKK2 Antibody (SR3035) [NBP3-27740] -

Western Blot: MEKK2 Antibody (SR3035) [NBP3-27740] - Western blot analysis of MEKK2 expression in HeLa cell lysate.

Immunohistochemistry-Paraffin: MEKK2 Antibody (SR3035) [NBP3-27740] -

Immunohistochemistry-Paraffin: MEKK2 Antibody (SR3035) [NBP3-27740] - Immunohistochemical analysis of paraffin-embedded human thyroid cancer

Applications for MEKK2 Antibody (SR3035)

Application
Recommended Usage

Flow Cytometry

1:50

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Immunoprecipitation

1:30

Western Blot

1:5000-1:20000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 150mM NaCl, 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MEKK2

MEKK2 is a Ser/Thr protein kinase belonging to the MEKK/STE11 subgroup of the MAP/ERK kinase kinase family (1). Closely related to MEKK3, MEKK2 is expressed in a multitude of tissues. MEKK2 directly phosphorylates and activates Ikappa B kinases and has been found to bind and activate protein kinase C-related kinase 2 (2). MEKK2 has also been known to activate JNK1/2, ERK1/2, p38, and ERK5 MAPK in vitro (3). MEKK2 interacting protein (Mip1) regulates MEKK2 expression (4).

Long Name

Mitogen-activated Protein Kinase Kinase Kinase 2

Alternate Names

MAP3K2, MAPKKK2

Gene Symbol

MAP3K2

Additional MEKK2 Products

Product Documents for MEKK2 Antibody (SR3035)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MEKK2 Antibody (SR3035)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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