MEKK4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-12324

Novus Biologicals, part of Bio-Techne
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NBP3-12324
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MEKK4 Antibodies »

Product Summary for MEKK4 Antibody

Immunogen

Synthetic peptide taken within amino acid region 1558-1608 on human MAP3K4 protein.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for MEKK4 Antibody

Immunohistochemistry-Paraffin: MEKK4 Antibody [NBP3-12324]

Immunohistochemistry-Paraffin: MEKK4 Antibody [NBP3-12324]

Immunohistochemistry-Paraffin: MEKK4 Antibody [NBP3-12324] - Mouse Heart. 1:50 dilution in IHC blocking buffer. DAB (brown) staining Hematoxylin QS (blue) counterstain. 40X magnification.
Immunohistochemistry-Paraffin: MEKK4 Antibody [NBP3-12324]

Immunohistochemistry-Paraffin: MEKK4 Antibody [NBP3-12324]

Immunohistochemistry-Paraffin: MEKK4 Antibody [NBP3-12324] - Mouse Heart. 1:50 dilution in IHC blocking buffer. DAB (brown) staining Hematoxylin QS (blue) counterstain. 10X magnification.

Applications for MEKK4 Antibody

Application
Recommended Usage

ELISA

1:10000

Immunohistochemistry

1:50-1:100

Immunohistochemistry-Paraffin

1:50-1:100

Immunoprecipitation

1:200

Western Blot

1:500
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.

Background: MEKK4

MEK kinase 4 (MEKK4), also known as MTK1, is a Ser/Thr protein kinase belonging to the MAP kinase kinase kinase family (1). This protein contains a protein kinase catalytic domain at the C-terminus. The N-terminal, non-kinase domain may contain a regulatory domain. MEKK4 regulates p38 and JNK, butnot ERK pathway, through the phosphorylation of the MAP2Ks MKK3 and MKK6 and MKK4 and MKK7 respectively (1-2).

Alternate Names

EC 2.7.11.25, FLJ42439, MAPKKK4yeast, homolog of, MEKK 4, mitogen-activated protein kinase kinase kinase 4

Gene Symbol

MAP3K4

Additional MEKK4 Products

Product Documents for MEKK4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MEKK4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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