Melan-A/MART-1 Antibody (MLANA/788) - IHC-Prediluted
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-48209
![Immunohistochemistry-Paraffin: Melan-A/MART-1 Antibody (MLANA/788) - IHC-Prediluted [NBP2-48209]](https://resources.bio-techne.com/images/products/Melan-A-MART-1-Antibody-MLANA-788-IHC-Prediluted-Immunohistochemistry-Paraffin-NBP2-48209-img0003.jpg "Immunohistochemistry-Paraffin: Melan-A/MART-1 Antibody (MLANA/788) - IHC-Prediluted [NBP2-48209]")
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Validated:
Human, Mouse, Rat, Canine
Applications
Immunohistochemistry, Immunohistochemistry-Paraffin
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 kappa Clone # MLANA/788
Format
IHC-Prediluted
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Summary for Melan-A/MART-1 Antibody (MLANA/788) - IHC-Prediluted
Immunogen
Recombinant human full-length Melan-A/MART-1 protein (Uniprot: Q16655)
Localization
Cytoplasmic
Specificity
This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This monoclonal antibody labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Marker
Melanoma Marker
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 kappa
Description
The prediluted antibody does not require any mixing, dilution, reconstitution, or titration; the antibody is ready-to-use and optimized for staining.
Scientific Data Images for Melan-A/MART-1 Antibody (MLANA/788) - IHC-Prediluted
Immunohistochemistry-Paraffin: Melan-A/MART-1 Antibody (MLANA/788) - IHC-Prediluted [NBP2-48209]
Immunohistochemistry-Paraffin: Melan-A/MART-1 Antibody (MLANA/788) - IHC-Prediluted [NBP2-48209] - Human Melanoma stained with Melan-A Monoclonal Antibody (MLANA/788).![Immunohistochemistry-Paraffin: Melan-A/MART-1 Antibody (MLANA/788) - IHC-Prediluted [NBP2-48209]](https://resources.bio-techne.com/images/products/Melan-A-MART-1-Antibody-MLANA-788-IHC-Prediluted-Immunohistochemistry-Paraffin-NBP2-48209-img0002.jpg "Immunohistochemistry-Paraffin: Melan-A/MART-1 Antibody (MLANA/788) - IHC-Prediluted [NBP2-48209]")
Immunohistochemistry-Paraffin: Melan-A/MART-1 Antibody (MLANA/788) - IHC-Prediluted [NBP2-48209]
Immunohistochemistry-Paraffin: Melan-A/MART-1 Antibody (MLANA/788) - IHC-Prediluted [NBP2-48209] - Human Testis stained with Melan-A Monoclonal Antibody (MLANA/788).Applications for Melan-A/MART-1 Antibody (MLANA/788) - IHC-Prediluted
Application
Recommended Usage
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry-Paraffin
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.
Use in Immunohistochemistry reported in scientific literature (PMID: 30606914).
Optimal dilution for a specific application should be determined.
Use in Immunohistochemistry reported in scientific literature (PMID: 30606914).
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
10 mM PBS with 0.05% BSA
Format
IHC-Prediluted
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C.
Background: Melan-A/MART-1
Alternate Names
Antigen LB39-AA, Antigen SK29-AA, MART-1, MelanA, MLANA
Gene Symbol
MLANA
Additional Melan-A/MART-1 Products
Product Documents for Melan-A/MART-1 Antibody (MLANA/788) - IHC-Prediluted
Product Specific Notices for Melan-A/MART-1 Antibody (MLANA/788) - IHC-Prediluted
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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