Melanocortin-3 R/MC3R Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-17738

Novus Biologicals, part of Bio-Techne
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NBP3-17738-100ul
NBP3-17738-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Rat (97%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Melanocortin-3 R/MC3R Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: FLFARLHVKRIAALPPADGVAPQQHSCMK

Reactivity Notes

Mouse (86%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Melanocortin-3 R/MC3R Antibody

Immunohistochemistry-Paraffin: Melanocortin-3 R/MC3R Antibody [NBP3-17738]

Immunohistochemistry-Paraffin: Melanocortin-3 R/MC3R Antibody [NBP3-17738]

Immunohistochemistry-Paraffin: Melanocortin-3 R/MC3R Antibody [NBP3-17738] - Staining of human hypothalamus shows strong cytoplasmic positivity in neuronal cells.

Applications for Melanocortin-3 R/MC3R Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Melanocortin-3 R/MC3R

Melanocortins are ligands for a subgroup of GPCRs positively coupled to Adenylate cylcases, termed as melanocortin receptors (MC1R, MC2R, MC3R, MC4R amd MC5R). These receptors are widely expressed at varied density throughout the body. The MC3R has been widely implicated in inflammation and is also implicated in a role in obesity and metabolism. MC3R KO mice exhibit reduced linear growth and lean mass and are hyperleptinemic and hyperinsulinemic.

Long Name

Melanocortin 3 Receptor

Alternate Names

MC3R, Melanocortin-3R, Melanocortin3R

Gene Symbol

MC3R

Additional Melanocortin-3 R/MC3R Products

Product Documents for Melanocortin-3 R/MC3R Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Melanocortin-3 R/MC3R Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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