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Melanocortin-4 R Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS4165

Novus Biologicals, part of Bio-Techne
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NLS4165

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Chimpanzee (100%), Orangutan (100%), Primate (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

Product Specifications

Immunogen

Synthetic 19 amino acid peptide from N-terminal extracellular domain of human Melanocortin-4 R.

Epitope

N-Terminus extracellular domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (95%), Tamarin (95%), Baboon (89%), Monkey (89%), Rat (84%), Equine (84%), Porcine (84%), Guinea (84%).

Localization

Cell Membrane (Multi-pass membrane protein).

Specificity

Human Melanocortin-4 R. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for Melanocortin-4 R Antibody - BSA Free

Immunohistochemistry-Paraffin: Melanocortin-4 R Antibody - BSA Free [NLS4165]

Immunohistochemistry-Paraffin: Melanocortin-4 R Antibody - BSA Free [NLS4165]

Immunohistochemistry-Paraffin: Melanocortin-4 R Antibody [NLS4165] - Analysis of anti-MC4 Receptor antibody with human brain, neurons and glia at 4 ug/ml.

Applications for Melanocortin-4 R Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

4 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: Melanocortin-4 R

Melanocortin 4 receptor (MC4R), a Melanocortin Receptor, has been shown to affect food intake and energy balance. Recently MC4R has been shown to modulate erectile function and sexual behavior (Van Der Ploeg et al. 2002). Expression of MC4R has been reported in brain. Unlike the other melanocortin receptors, MC4R is not expressed in adrenal cortex or in melanocytes.

Long Name

Melanocortin 4 Receptor

Alternate Names

Fatboy, Glu3, MC4R, Melanocortin-4R, Melanocortin4R

Entrez Gene IDs

4160 (Human)

Gene Symbol

MC4R

UniProt

Additional Melanocortin-4 R Products

Product Documents for Melanocortin-4 R Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Melanocortin-4 R Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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