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Mer Antibody (3D07) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB110-94148

Novus Biologicals, part of Bio-Techne
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NB110-94148
NB110-94148-0.025mg

Key Product Details

Species Reactivity

Validated:

Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG1 Clone # 3D07

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

Product Summary for Mer Antibody (3D07) - Azide and BSA Free

Immunogen

Recombinant Mouse Mer extracellular domain

Specificity

It has no cross-reactivity with recombinant mouse Axl or recombinant mouse Dtk.

Clonality

Monoclonal

Host

Rat

Isotype

IgG1

Scientific Data Images for Mer Antibody (3D07) - Azide and BSA Free

Immunohistochemistry-Paraffin: Mer Antibody (3D07) - Azide and BSA Free [NB110-94148]

Immunohistochemistry-Paraffin: Mer Antibody (3D07) - Azide and BSA Free [NB110-94148]

Immunohistochemistry-Paraffin: Mer Antibody (3D07) [NB110-94148] - Mer immunohistochemistry staining of paraffin sections of mouse lung and spleen tissues from LPS exposed animals.

Applications for Mer Antibody (3D07) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:50-1:200

Western Blot

1:100-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Reconstitution

Reconstitute with sterilized PBS to a final concentration of 0.2 mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Mer

MerTK (c-mer, Nyk, Eyk) is a tyrosine kinase that belongs to a family of transmembrane receptors (1). MerTk has been implicated in reversible cell growth arrest, survival, proliferation and cell adhesion. Growth arrest specific protein 6 (Gas6) is an activating ligand for MerTK (2-3). MerTK is required for clearance of apoptotic cells by mononuclear phagocytes in mice; with its absence resulting in progressive lupus like autoimmunity (4). Defects in MERTK are a cause of retinitis pigmentosa (RP) (5).

Long Name

Receptor Tyrosine Protein Kinase Mer

Alternate Names

c-Eyk, C-mer, MerTK

Entrez Gene IDs

17289 (Mouse)

Gene Symbol

MERTK

UniProt

Additional Mer Products

Product Documents for Mer Antibody (3D07) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Mer Antibody (3D07) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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