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Key Product Details

Species Reactivity

Virus

Applications

Serum

Label

Janelia Fluor 635

Antibody Source

Monoclonal Mouse IgG1 Clone # HMPV57

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Sub-type A hMPV virus isolate NCL03-4/174

Specificity

NBP1-25941 recognises human metapneumovirus (hMPV), a member of the Paramyxoviridae RNA virus family. Metapneumovirus was discovered in 2001 and is distributed worldwide. Infection in the upper respiratory tract is associated with mild illness, while lower respiratory tract infection can cause fever, cough, pneumonia, bronchiolitis and wheezing. Severe lower respiratory tract infection is most common in the very young, the very old and the immunosuppressed. Metapneumovirus is a common cause of respiratory infection.Phylogenetic analysis has shown two major genotypes, A and B, each containing two sub-divisions, suggesting that four distinct lineages circulate in the population with different lineages predominating in different years. NBP1-25941 recognises all sub-types (A1, A2, B1 and B2) of hMPVNBP1-25941 does not cross-react with cell cultures infected with hRSV, influenzaviruses A and B, adenovirus, parainfluenza viruses 1, 2, 3 and 4b, mumps virus, measles virus, varicella-zoster virus, herpes simplex virus types 1 and 2, human cytomegalovirus, human herpesvirus type 6, ECHOvirus 19, Coxsachievirus B4, poliovirus types 1-3, HHV6 or uninfected HeLa, MA104, 3MK, LLC-MK, HEp2, MRC-5 and HSB-2 cells. It also does not react with sputum bacteria.The target antigen has not been determined for this antibody.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Meta-Pneumovirus Antibody (HMPV57) [Janelia Fluor® 635]

Application
Recommended Usage

Serum

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Meta-Pneumovirus

Human metapneumovirus (hMPV) was discovered in 2001, and has been identified worldwide. hMPV is a common respiratory pathogen, particularly in infants and young children. The virus is associated with both upper and lower respiratory tract infections and may be a trigger for asthma. At least two major genotypes of hMPV circulate during community outbreaks.

Alternate Names

hMPV, metapneumovirus

Gene Symbol

GLYG

Additional Meta-Pneumovirus Products

Product Documents for Meta-Pneumovirus Antibody (HMPV57) [Janelia Fluor® 635]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Meta-Pneumovirus Antibody (HMPV57) [Janelia Fluor® 635]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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