mGluR2/3 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1760

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Rat

Cited:

Rat

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all mGluR2/3 Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to residues 860-875 of the rat mGlurR2/3 protein.

Reactivity Notes

Predicted react to human and Mouse.

Specificity

metabotropic Glutamate Receptor 2/3

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for mGluR2/3 Antibody - BSA Free

Western Blot: mGluR2/3 AntibodyBSA Free [NB100-1760]

Western Blot: mGluR2/3 AntibodyBSA Free [NB100-1760]

Western Blot: mGluR2/3 Antibody [NB100-1760] - Analysis of rat brain shows bands migrating at M r =100,000 and 190,000 which may be a dimer of the smaller band.

Applications for mGluR2/3 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500
Application Notes
*Investigator should determine optimal dilution for each application.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: mGluR2/3

Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8. mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain.

Long Name

Metabotropic Glutamate Receptor 2 and 3

Alternate Names

GLUR2, glutamate metabotropic receptor 2, glutamate receptor, metabotropic 2, GPRC1Bmetabotropic glutamate receptor 2, mGlu2, mGluR2, MGLUR2glutamate receptor homolog

Entrez Gene IDs

24415 (Rat)

Gene Symbol

GRM2

UniProt

P31421 (Rat)

Additional mGluR2/3 Products

Product Documents for mGluR2/3 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for mGluR2/3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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