mGluR2 Antibody (S04-2D1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19688

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-19688-100ul
NBP3-19688-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S04-2D1

Concentration

0.3 mg/ml

View all mGluR2 Antibodies »

Product Summary for mGluR2 Antibody (S04-2D1)

Immunogen

A synthetic peptide of human mGluR2 (Uniprot # Q14416)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

99 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for mGluR2 Antibody (S04-2D1)

Western Blot: mGluR2 Antibody (S04-2D1) [NBP3-19688]

Western Blot: mGluR2 Antibody (S04-2D1) [NBP3-19688]

Western Blot: mGluR2 Antibody (S04-2D1) [NBP3-19688] - Western blot detection of mGluR2 in K562, Hela cell lysates using NBP3-19688 (1:1000 diluted). Predicted band size: 99kDa. Observed band size: 99kDa.

Applications for mGluR2 Antibody (S04-2D1)

Application
Recommended Usage

Western Blot

1/2000-1/10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: mGluR2

The Metabotropic Glutamate Receptor GRM2 binds L-glutamate and has been linked to the inhibition of the cyclic AMP signaling cascade. GRM2 is involved in mediating the suppression of neurotransmission and in synaptogenesis and synaptic stabilization. Glutamatergic neurotransmission plays a role in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. GRM2 has been reported in various regions of the human and animal brain, as well as in rat eye and spinal cord. ESTs have been isolated from brain and testis libraries. Caution: GLUR2 refers to Ionotropic Glutamate Receptor 2, not to Metabotropic Glutamate Receptor 2 (mGLUR2).

Long Name

Metabotropic Glutamate Receptor 2

Alternate Names

GPRC1B, GRM2, mGluR7

Gene Symbol

GRM2

Additional mGluR2 Products

Product Documents for mGluR2 Antibody (S04-2D1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for mGluR2 Antibody (S04-2D1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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