mGluR6 Antibody (4C11E12) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-61851

Novus Biologicals, part of Bio-Techne
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NBP2-61851
NBP2-61851-0.025ml
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 4C11E12

Format

BSA Free

Concentration

1 mg/ml

View all mGluR6 Antibodies »

Product Specifications

Immunogen

Purified recombinant fragment of human mGluR6 (AA: extra 480-585) expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

95.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for mGluR6 Antibody (4C11E12) - BSA Free

Western Blot: mGluR6 Antibody (4C11E12)BSA Free [NBP2-61851]

Western Blot: mGluR6 Antibody (4C11E12)BSA Free [NBP2-61851]

Western Blot: mGluR6 Antibody (4C11E12) [NBP2-61851] - Analysis using GRM6 mAb against human GRM6 (AA: extra 480-585) recombinant protein. (Expected MW is 37.5 kDa)
Western Blot: mGluR6 Antibody (4C11E12)BSA Free [NBP2-61851]

Western Blot: mGluR6 Antibody (4C11E12)BSA Free [NBP2-61851]

Western Blot: mGluR6 Antibody (4C11E12) [NBP2-61851] - Analysis using GRM6 mAb against HEK293 (1) and GRM6 (AA: extra 480-585)-hIgGFc transfected HEK293 (2) cell lysate.
ELISA: mGluR6 Antibody (4C11E12) - BSA Free [NBP2-61851]

ELISA: mGluR6 Antibody (4C11E12) - BSA Free [NBP2-61851]

ELISA: mGluR6 Antibody (4C11E12) [NBP2-61851] - Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Applications for mGluR6 Antibody (4C11E12) - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1:100-1:2000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: mGluR6

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

Long Name

Metabotropic Glutamate Receptor 6

Alternate Names

Gm3, GPRC1F, GRM6

Gene Symbol

GRM6

Additional mGluR6 Products

Product Documents for mGluR6 Antibody (4C11E12) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for mGluR6 Antibody (4C11E12) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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