MHC Class II Antibody (CVS20)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-34848

Novus Biologicals, part of Bio-Techne
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NBP2-34848-0.025mg
NBP2-34848
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Key Product Details

Species Reactivity

Validated:

Equine

Cited:

Human

Applications

Validated:

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, Immunoprecipitation

Cited:

Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CVS20

Concentration

1.0 mg/ml

View all MHC Class II Antibodies »

Product Specifications

Immunogen

3132 cells

Reactivity Notes

Predicted cross-reactivities: Human, Dog, Bovine

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for MHC Class II Antibody (CVS20)

Flow Cytometry: MHC Class II Antibody (CVS20) - BSA Free [NBP2-34848]

Flow Cytometry: MHC Class II Antibody (CVS20) - BSA Free [NBP2-34848]

Flow Cytometry: MHC Class II Antibody (CVS20) [NBP2-34848] - MHC Class II expression in human PBMCs. Image from verified customer review.
Flow Cytometry: MHC Class II Antibody (CVS20) - BSA Free [NBP2-34848]

Flow Cytometry: MHC Class II Antibody (CVS20) - BSA Free [NBP2-34848]

Flow Cytometry: MHC Class II Antibody (CVS20) [NBP2-34848] - Staining of equine peripheral blood lymphocytes

Applications for MHC Class II Antibody (CVS20)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Frozen

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 5 using NBP2-34848 in the following applications:

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MHC Class II

MHC Class II antigens are heterodimers consisting of one alpha chain(31-34kD) and one beta chain (26-29kD). The family of monoclonal antibodies (ER-TR 3, ER-TR 2, ER-TR 1) detect MHC class II antigens encoded by the murine Ia region of the H-2 complex, corresponding to the human HLA-DR region. MHC Class II antigens are a valuable tool for studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these antibodies also stain stromal cells in the thymus. MHC Class II antigens are also inducible on a number of other cells (endothelium and epithelial cells) by interferon gamma.

Alternate Names

class II histocompatibility antigen, M alpha chain, D6S222E, DMA, HLA class II histocompatibility antigen, DM alpha chain, major histocompatibility complex, class II, DM alpha, MHC class II antigen DMA, Really interesting new gene 6 protein, RING6HLADM

Gene Symbol

HLA-DMA

Additional MHC Class II Products

Product Documents for MHC Class II Antibody (CVS20)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for MHC Class II Antibody (CVS20)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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