MHC Class II Antibody (CVS20) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-34848

Novus Biologicals, part of Bio-Techne
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NBP2-34848-0.025mg
NBP2-34848
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Key Product Details

Species Reactivity

Validated:

Equine

Cited:

Human

Applications

Validated:

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, Immunoprecipitation

Cited:

Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CVS20

Format

BSA Free

Concentration

1.0 mg/ml

View all MHC Class II Antibodies »

Product Specifications

Immunogen

3132 cells

Reactivity Notes

Predicted cross-reactivities: Human, Dog, Bovine

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for MHC Class II Antibody (CVS20) - BSA Free

Flow Cytometry: MHC Class II Antibody (CVS20) - BSA Free [NBP2-34848]

Flow Cytometry: MHC Class II Antibody (CVS20) - BSA Free [NBP2-34848]

Flow Cytometry: MHC Class II Antibody (CVS20) [NBP2-34848] - MHC Class II expression in human PBMCs. Image from verified customer review.
Flow Cytometry: MHC Class II Antibody (CVS20) - BSA Free [NBP2-34848]

Flow Cytometry: MHC Class II Antibody (CVS20) - BSA Free [NBP2-34848]

Flow Cytometry: MHC Class II Antibody (CVS20) [NBP2-34848] - Staining of equine peripheral blood lymphocytes

Applications for MHC Class II Antibody (CVS20) - BSA Free

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Frozen

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 5 using NBP2-34848 in the following applications:

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MHC Class II

MHC Class II antigens are heterodimers consisting of one alpha chain(31-34kD) and one beta chain (26-29kD). The family of monoclonal antibodies (ER-TR 3, ER-TR 2, ER-TR 1) detect MHC class II antigens encoded by the murine Ia region of the H-2 complex, corresponding to the human HLA-DR region. MHC Class II antigens are a valuable tool for studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these antibodies also stain stromal cells in the thymus. MHC Class II antigens are also inducible on a number of other cells (endothelium and epithelial cells) by interferon gamma.

Alternate Names

class II histocompatibility antigen, M alpha chain, D6S222E, DMA, HLA class II histocompatibility antigen, DM alpha chain, major histocompatibility complex, class II, DM alpha, MHC class II antigen DMA, Really interesting new gene 6 protein, RING6HLADM

Gene Symbol

HLA-DMA

Additional MHC Class II Products

Product Documents for MHC Class II Antibody (CVS20) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for MHC Class II Antibody (CVS20) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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