MiRP2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-49885

Novus Biologicals, part of Bio-Techne
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NBP1-49885
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Key Product Details

Species Reactivity

Human, Mouse, Rat, Bovine, Canine

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all MiRP2 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-PDNQTEERRASLP corresponding to internal region according to NP_005463.1.

Epitope

PDNQTEERRASLP - Internal region

Reactivity Notes

Expected from sequence similarity: Mouse, Rat, Canine, Bovine, Porcine

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for MiRP2 Antibody

Immunohistochemistry-Paraffin: MiRP2 Antibody [NBP1-49885]

Immunohistochemistry-Paraffin: MiRP2 Antibody [NBP1-49885]

Immunohistochemistry-Paraffin: MiRP2 Antibody [NBP1-49885] - 3.75ug/ml staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Applications for MiRP2 Antibody

Application
Recommended Usage

Immunohistochemistry

1ug/ml

Peptide ELISA

Detection limit 1:1000

Western Blot

detection limit 1:1000
Application Notes
Western blot: Preliminary experiments in Human, Mouse and Rat Skeletal Muscle lysates gave no specific signal but low background
IHC: Paraffin embedded Human Kidney.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: MiRP2

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis. (provided by RefSeq)

Alternate Names

cardiac voltage-gated potassium channel accessory subunit, DKFZp781H21101, HOKPPMGC102685, HYPP, MGC129924, Minimum potassium ion channel-related peptide 2, MinK-related peptide 2, MiRP2, Potassium channel subunit beta MiRP2, potassium voltage-gated channel subfamily E member 3, potassium voltage-gated channel, Isk-related family, member 3, voltage-gated K+ channel subunit MIRP2

Entrez Gene IDs

10008 (Human); 57442 (Mouse); 63883 (Rat)

Gene Symbol

KCNE3

UniProt

NP_005463.1 (Human)

Additional MiRP2 Products

Product Documents for MiRP2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MiRP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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