MIS/AMH Antibody (AMH/6713R)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-07296

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # AMH/6713R

Concentration

0.2 mg/ml

View all MIS/AMH Antibodies »

Product Summary for MIS/AMH Antibody (AMH/6713R)

Immunogen

A synthetic peptide from the C-terminus of human MIS/AMH (aa 460-560) (exact sequence is proprietary) (Uniprot: IDP03971)

Localization

Secreted

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-08459)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C.

Scientific Data Images for MIS/AMH Antibody (AMH/6713R)

Immunohistochemistry-Paraffin: MIS/AMH Antibody (AMH/6713R) [NBP3-07296]

Immunohistochemistry-Paraffin: MIS/AMH Antibody (AMH/6713R) [NBP3-07296]

Immunohistochemistry-Paraffin: MIS/AMH Antibody (AMH/6713R) [NBP3-07296] - IHC analysis of formalin-fixed, paraffin-embedded human kidney. MIS/AMH antibody (AMH/6713R) at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. 2 : HRP-polymer, 30min. DAB, 5min.
Immunohistochemistry-Paraffin: MIS/AMH Antibody (AMH/6713R) [NBP3-07296]

Immunohistochemistry-Paraffin: MIS/AMH Antibody (AMH/6713R) [NBP3-07296]

Immunohistochemistry-Paraffin: MIS/AMH Antibody (AMH/6713R) [NBP3-07296] - IHC analysis of formalin-fixed, paraffin-embedded human bladder carcinoma. MIS/AMH antibody (AMH/6713R) at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. 2 : HRP-polymer, 30min. DAB, 5min.
Immunohistochemistry-Paraffin: MIS/AMH Antibody (AMH/6713R) [NBP3-07296]

Immunohistochemistry-Paraffin: MIS/AMH Antibody (AMH/6713R) [NBP3-07296]

Immunohistochemistry-Paraffin: MIS/AMH Antibody (AMH/6713R) [NBP3-07296] - IHC analysis of formalin-fixed, paraffin-embedded human cerebral cortex. Negative tissue control using MIS/AMH antibody (AMH/6713R) at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. 2 : HRP-polymer, 30min. DAB, 5min.

Applications for MIS/AMH Antibody (AMH/6713R)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: MIS/AMH

Müllerian inhibiting substance (MIS), also named anti-Müllerian hormone (AMH), is a tissue-specific TGF-beta superfamily growth factor. Its expression is restricted to Sertoli cells of fetal and postnatal testis, and to granulosa cells of postnatal ovary. MIS is synthesized and secreted as a disulfide-linked homodimeric propeptide. Proteolytic cleavage is required to separate the N-terminal proregion from the C-terminal bioactive peptide. Both fragments remain associated in a non-covalent complex. The C-terminal sequence forms a cysteine knot via seven canonical cysteine residues found in TGF-beta superfamily members.

Long Name

Mullerian-inhibiting Substance/Anti-Mullerian Hormone

Alternate Names

AMH

Gene Symbol

AMH

Additional MIS/AMH Products

Product Documents for MIS/AMH Antibody (AMH/6713R)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MIS/AMH Antibody (AMH/6713R)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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