MIS RII/AMHR2 Antibody (8Z8X4)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-16706

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-16706-100ul
NBP3-16706-20ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 8Z8X4

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MIS RII Antibodies »

Product Summary for MIS RII/AMHR2 Antibody (8Z8X4)

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human MIS RII/AMHR2 (NP_065434.1). PRAIRCLYSRCCFGIWNLTQDRAQVEMQGCRDSDEPGCESLHCDPSPRAHPSPGSTLFTCSCGTDFCNANYSHLPPPGSPGTPGSQGPQAAPGESIWMALV

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MIS RII/AMHR2 Antibody (8Z8X4)

Western Blot: MIS RII/AMHR2 Antibody (8Z8X4) [NBP3-16706]

Western Blot: MIS RII/AMHR2 Antibody (8Z8X4) [NBP3-16706]

Western Blot: MIS RII/AMHR2 Antibody (8Z8X4) [NBP3-16706] - Western blot analysis of extracts of various cell lines, using MIS RII/AMHR2 Rabbit mAb (NBP3-16706) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3min.

Applications for MIS RII/AMHR2 Antibody (8Z8X4)

Application
Recommended Usage

Western Blot

1:500 - 1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 0.05% BSA, 50% glycerol, pH7.3

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: MIS RII

AMHR2 is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins that is expressed in fetal and adult gonads of both sexes. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth; anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. A number of allelic variants of AMHR2 are associated with persistent mullerian duct syndrome.

Long Name

Mullerian-Inhibiting Substance Type II Receptor

Alternate Names

AMHR2, AMHRII, C14, MISR2, MISRII

Gene Symbol

AMHR2

Additional MIS RII Products

Product Documents for MIS RII/AMHR2 Antibody (8Z8X4)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for MIS RII/AMHR2 Antibody (8Z8X4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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