MLL5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-17395

Novus Biologicals, part of Bio-Techne
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NBP3-17395-100ul
NBP3-17395-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (91%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MLL5 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTASGFCPHPGSVALPHGVQGPQQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MLL5 Antibody

Immunocytochemistry/ Immunofluorescence: MLL5 Antibody [NBP3-17395]

Immunocytochemistry/ Immunofluorescence: MLL5 Antibody [NBP3-17395]

Immunocytochemistry/Immunofluorescence: MLL5 Antibody [NBP3-17395] - Staining of human cell line RT4 shows localization to nucleoplasm & nuclear bodies.

Applications for MLL5 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence, PFA/Triton X-100 is recommended for fixation/permeabilization.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MLL5

MLL5 is a divergent member of the Drosophila Trithorax related SET and PHD domain containing chromatin regulators that are involved in the regulation of transcriptional "memory" during differentiation. Human MLL5 is located on chromosome 7q22, that is frequently deleted in myeloid leukemias. Inactivation of the Mll5 gene in mice results in a reduction in the average representation of hematopoietic stem cells, and in functional impairment of long term hematopoietic repopulation potential under competitive conditions. Overexpression of the protein also inhibits cell cycle progression.

Alternate Names

EC 2.1.1.43, FLJ10078, HDCMC04P, histone-lysine N-methyltransferase MLL5, KMT2EFLJ14026, Lysine N-methyltransferase 2E, MGC70452, myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila), Myeloid/lymphoid or mixed-lineage leukemia protein 5

Gene Symbol

KMT2E

Additional MLL5 Products

Product Documents for MLL5 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MLL5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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