MLLT1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-84840

Novus Biologicals, part of Bio-Techne
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NBP1-84840
NBP1-84840-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MLLT1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: MVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKE

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (84%), Rat (84%). Human reactivity reported in scientific literature (PMID: 26635203).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MLLT1 Antibody

Immunocytochemistry/ Immunofluorescence: MLLT1 Antibody [NBP1-84840]

Immunocytochemistry/ Immunofluorescence: MLLT1 Antibody [NBP1-84840]

Immunocytochemistry/Immunofluorescence: MLLT1 Antibody [NBP1-84840] - Staining of human cell line U-251 MG shows localization to nucleoplasm & nucleoli fibrillar center.
Immunohistochemistry-Paraffin: MLLT1 Antibody [NBP1-84840]

Immunohistochemistry-Paraffin: MLLT1 Antibody [NBP1-84840]

Immunohistochemistry-Paraffin: MLLT1 Antibody [NBP1-84840] - Staining of human hippocampus shows strong cytoplasmic and nucleolar positivity in neuronal cells.

Applications for MLLT1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
WB reported in scientific literature (PMID: 26635203). For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MLLT1

MLLT1, also known as ENL (eleven nineteen leukemia protein), was originally identified as a gene involved in a recurrent translocation (11;19) with the mixed-lineage leukemia (MLL) gene. The MLL-ENL fusion protein has been found to associate with SWI/SNF complexes and promote transcription from the HoxA7 promoter. Additionally, from studies to identify proteins that associate with MLLT1, MLLT1 is suggested to play a role in histone modification and transcriptional elongation.

Alternate Names

ENLENL/MLL fusion, LTG19MLLT1/MLL fusion, myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog);translocated to, 1, myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila);translocated to, 1, protein ENL, YEATS domain-containing protein 1, YEATS1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocatedto, 1

Gene Symbol

MLLT1

Additional MLLT1 Products

Product Documents for MLLT1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MLLT1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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