MLLT11 Antibody (2A9-1B7)

Novus Biologicals, part of Bio-Techne | Catalog # H00010962-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 2A9-1B7

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MLLT11 Antibodies »

Product Specifications

Immunogen

AF1Q (AAH09624, 1 a.a. ~ 90 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MRDPVSSQYSSFLFWRMPIPELDLSELEGLGLSDTATYKVKDSSVGKMIGQATAADQEKNPEGDGLLEYSTFNFWRAPIASIHSFELDLL

Reactivity Notes

Other species not tested.

Specificity

MLLT11 - ALL1-fused gene from chromosome 1q

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for MLLT11 Antibody (2A9-1B7)

ELISA: MLLT11 Antibody (2A9-1B7) [H00010962-M01]

ELISA: MLLT11 Antibody (2A9-1B7) [H00010962-M01]

ELISA: MLLT11 Antibody (2A9-1B7) [H00010962-M01] - Detection limit for recombinant GST tagged MLLT11 is approximately 1ng/ml as a capture antibody.
ELISA: MLLT11 Antibody (2A9-1B7) [H00010962-M01]

ELISA: MLLT11 Antibody (2A9-1B7) [H00010962-M01]

ELISA: MLLT11 Antibody (2A9-1B7) [H00010962-M01] - Detection limit for recombinant GST tagged MLLT11 is approximately 0.03ng/ml as a capture antibody.

Applications for MLLT11 Antibody (2A9-1B7)

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1:500
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: MLLT11

The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1;11)(q21;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested.

Alternate Names

AF1QRP11-316M1.10, ALL1 fused gene from chromosome 1q, ALL1-fused gene from chromosome 1q, myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila);translocated to, 11, protein AF1q

Entrez Gene IDs

10962 (Human)

Gene Symbol

MLLT11

OMIM

604684 (Human)

UniProt

AAH09624 (Human)

Additional MLLT11 Products

Product Documents for MLLT11 Antibody (2A9-1B7)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MLLT11 Antibody (2A9-1B7)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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