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Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Human, Mouse

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 1043 and 1093 of human AF17 (MLLT6, myeloid/lymphoid or mixed-lineage leukemia translocated to, 6 ) using the numbering given in entry NP_005928.2 (GeneID 4302).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MLLT6 Antibody

Western Blot: MLLT6 Antibody [NBP1-22995]

Western Blot: MLLT6 Antibody [NBP1-22995]

Western Blot: MLLT6 Antibody [NBP1-22995] - AF17 by Western Blot (h&m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) and mouse NIH3T3 (M; 50 mcg) cells. Antibodies: Affinity purified rabbit anti-AF17 antibody A302-198A used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. AF17 was also immunoprecipitated by rabbit anti-AF17 antibody BL8668, which recognizes an upstream epitope.

Applications for MLLT6 Antibody

Application
Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: MLLT6

AF17 was discovered as part of a genetic rearrangement in the MLL (mixed lineage leukemia) gene associated with acute myeloid leukemia. AF17 is also known as MLLT6.

Alternate Names

AF17Myeloid/lymphoid or mixed-lineage leukemia, translocated to, 6, ALL1-fused gene from chromosome 17 protein, FLJ23480, myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog);translocated to, 6, myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocatedto, 6, myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila);translocated to, 6, protein AF-17, trithorax homolog

Entrez Gene IDs

4302 (Human)

Gene Symbol

MLLT6

UniProt

Additional MLLT6 Products

Product Documents for MLLT6 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MLLT6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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