MMADHC Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38351

Novus Biologicals, part of Bio-Techne
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NBP2-38351
NBP2-38351-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (93%), Rat (91%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MMADHC Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: TLPDVLAEPLSSERHEFVMAQYVNEFQGNDAPVEQEINSAETYFESARVECAIQTCPELLRKDFESLFPEVANGKLMILTVTQKTKNDMTVWSEEV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MMADHC Antibody

Western Blot: MMADHC Antibody [NBP2-38351]

Western Blot: MMADHC Antibody [NBP2-38351]

Western Blot: MMADHC Antibody [NBP2-38351] - Analysis in human cell line K562.
Immunohistochemistry-Paraffin: MMADHC Antibody [NBP2-38351]

Immunohistochemistry-Paraffin: MMADHC Antibody [NBP2-38351]

Immunohistochemistry-Paraffin: MMADHC Antibody [NBP2-38351] - Staining of human liver shows moderate cytoplasmic positivity in hepatocytes.
Immunohistochemistry-Paraffin: MMADHC Antibody [NBP2-38351]

Immunohistochemistry-Paraffin: MMADHC Antibody [NBP2-38351]

Immunohistochemistry-Paraffin: MMADHC Antibody [NBP2-38351] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules and cells in glomeruli.
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Applications for MMADHC Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MMADHC

MMADHC encodes a mitochondrial protein that is involved in an early step of vitamin B12 metabolism. Vitamin B12 (cobalamin) is essential for normal development and survival in humans. Mutations in this gene cause methylmalonic aciduria and homocystinuria type cblD (MMADHC), a disorder of cobalamin metabolism that is characterized by decreased levels of the coenzymes adenosylcobalamin and methylcobalamin. Pseudogenes have been identified on chromosomes 11 and X.

Alternate Names

cblD, chromosome 2 open reading frame 25, methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria, mitochondrial, protein C2orf25, mitochondrial

Gene Symbol

MMADHC

UniProt

Q9H3L0 (Human)

Additional MMADHC Products

Product Documents for MMADHC Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MMADHC Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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