Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24. (provided by RefSeq)

Long Name

Matrix Metalloproteinase 24/Membrane Type 5 MMP

Alternate Names

MMP24, MT5-MMP

Gene Symbol

MMP24

UniProt

Q9R0S2

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Product Documents for MMP-24/MT5-MMP Antibody (RM0289-7J71) - Azide and BSA Free

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Product Specific Notices for MMP-24/MT5-MMP Antibody (RM0289-7J71) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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MMP-24/MT5-MMP Antibody (RM0289-7J71) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-11803

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Applications for MMP-24/MT5-MMP Antibody (RM0289-7J71) - Azide and BSA Free

Flow Cytometry

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Background: MMP-24/MT5-MMP