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MMP-24/MT5-MMP Antibody (RM0289-7J71) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-11803

Novus Biologicals, part of Bio-Techne
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NBP2-11803
NBP2-11803-0.025mg
Conjugate
Catalog #

Key Product Details

Species Reactivity

Validated:

Mouse

Applications

CyTOF-ready, Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2 Clone # RM0289-7J71

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

Product Summary for MMP-24/MT5-MMP Antibody (RM0289-7J71) - Azide and BSA Free

Immunogen

Mouse recombinant MMP-24/MT5-MMP (extracellular domain)

Specificity

This antibody weakly cross reacts with mouse MMP3 and MMP-9.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2

Applications for MMP-24/MT5-MMP Antibody (RM0289-7J71) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

1:10-1:1000

Western Blot

1:100-1:500
Application Notes
This antibody is Cytof ready.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Reconstitution

Reconstitute with sterilized PBS to a final concentration of 0.5 mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MMP-24/MT5-MMP

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24. (provided by RefSeq)

Long Name

Matrix Metalloproteinase 24/Membrane Type 5 MMP

Alternate Names

MMP24, MT5-MMP

Gene Symbol

MMP24

UniProt

Additional MMP-24/MT5-MMP Products

Product Documents for MMP-24/MT5-MMP Antibody (RM0289-7J71) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MMP-24/MT5-MMP Antibody (RM0289-7J71) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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