MMP-3 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB100-91878

Novus Biologicals, part of Bio-Techne
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NB100-91878
NB100-91878SS
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human, Mouse, Rat

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

IF/IHC, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all MMP-3 Antibodies »

Product Specifications

Immunogen

A synthetic peptide made to an C-terminal portion of the human MMP3 protein (between residues 400-477) [UniProt P08254]

Reactivity Notes

Human, Mouse and Rat.

Marker

Mesenchymal Cells Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for MMP-3 Antibody - BSA Free

Western Blot: MMP-3 AntibodyBSA Free [NB100-91878]

Western Blot: MMP-3 AntibodyBSA Free [NB100-91878]

Western Blot: MMP-3 Antibody [NB100-91878] - Analysis of MMP-3 (S453) antibody in extracts from 293 cells.
Immunohistochemistry-Paraffin: MMP-3 Antibody - BSA Free [NB100-91878]

Immunohistochemistry-Paraffin: MMP-3 Antibody - BSA Free [NB100-91878]

Immunohistochemistry-Paraffin: MMP-3 Antibody [NB100-91878] - Analysis of mouse brain.
Immunohistochemistry-Paraffin: MMP-3 Antibody - BSA Free [NB100-91878]

Immunohistochemistry-Paraffin: MMP-3 Antibody - BSA Free [NB100-91878]

Immunohistochemistry-Paraffin: MMP-3 Antibody [NB100-91878] - Analyzes of paraffin-embedded human breast carcinoma tissue.

Applications for MMP-3 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Immunohistochemistry-Paraffin

1:50-1:100

Western Blot

1:500- 1:1000
Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 4 using NB100-91878 in the following applications:

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MMP-3

Matrix metalloproteinase 3 (MMP3), also known as Stromelysin-1, SL-1, and STMY1, is a member of the matrix metalloproteinase (MMP) family. Members of the MMP family are involved in the breakdown of the extracellular matrix in response to normal physiological and disease processes; these processes include embryonic development, reproduction, tissue remodeling, arthritis and metastasis. The majority of MMP proteins are secreted into the extracellular matrix as inactive proproteins; they are activated when cleaved by an extracellular proteinase. The MMP3 gene contains four hemopexin-like domains, and is part of a cluster of MMP genes that localize to chromosome 11q22.3. This gene encodes the MMP3 enzyme that degrades fibronectin, laminin, gelatins (type I, III, IV and V), collagens (type III, IV, X, and IX), and cartilage proteoglycans. Additionally, the MMP3 enzyme activates procollagenase. Areas of interest for MMP3 include wound repair, progression of atherosclerosis, and tumor initiation.

Long Name

Matrix Metalloproteinase 3

Alternate Names

MMP3, Stromelysin 1

Entrez Gene IDs

4314 (Human); 17392 (Mouse); 171045 (Rat)

Gene Symbol

MMP3

UniProt

P08254, P28862

Additional MMP-3 Products

Product Documents for MMP-3 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MMP-3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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