This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for MMP26 Antibody

Immunocytochemistry/ Immunofluorescence: MMP26 Antibody [NBP3-00124]

Immunocytochemistry/Immunofluorescence: MMP26 Antibody [NBP3-00124] - Immunofluorescence staining of MMP26 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human MMP26 polyclonal antibody (dilution ratio: 1:1000) at 4C overnight. Then cells were stained with the Alexa Fluor(R)488-conjugated Goat Anti-rabbit IgG Secondary antibody (green)Positive staining was localized to cytoplasm.

Immunohistochemistry-Paraffin: MMP26 Antibody [NBP3-00124]

Immunohistochemistry-Paraffin: MMP26 Antibody [NBP3-00124] - Staining of human MMP26 in human placenta with rabbit polyclonal antibody at 1:500 dilution.

Applications for MMP26 Antibody

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:300-1:10000

Immunohistochemistry-Paraffin

1:200-1:1000

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MMP-26

Matrix metalloproteinase 26 (MMP-26) is specifically expressed in cancer cells of epithelial origin, including carcinomas of lung, prostate and breast. Several unique structural and regulatory features, including an unusual 'cysteine-switch' motif, discriminate broad-spectrum MMP-26 from most other MMPs. MMP-26 efficiently cleaves fibrinogen and extracellular matrix proteins, including fibronectin, vitronectin and denatured collagen (1). Expression analysis revealed that matrilysin-2 is detected not only in placenta and uterus but is widely expressed in malignant tumors from different sources as well as in diverse tumor cell lines. These data together with its broad spectrum of proteolytic activity, suggest that MMP-26 may play a role in some of the tissue-remodeling events associated with tumor progression (2). A study of MMP-26 mRNA steady states levels reveals, among the tissue examined, a specific expression in placenta. MMP-26 mRNA could also be detected in several human cell lines such as HEK 293 kidney cells and HFB1 lymphoma cells (3)

Long Name

Matrix Metalloproteinase 26

Alternate Names

Endometase, Matrilysin 2, MMP26

Gene Symbol

MMP26

Additional MMP-26 Products

Product Documents for MMP26 Antibody

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for MMP26 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

MMP26 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-00124

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

Concentration

View all MMP-26 Antibodies »

Product Specifications

Immunogen

Clonality

Host

Isotype

Description

Scientific Data Images for MMP26 Antibody

Immunocytochemistry/ Immunofluorescence: MMP26 Antibody [NBP3-00124]

Immunohistochemistry-Paraffin: MMP26 Antibody [NBP3-00124]

Applications for MMP26 Antibody

Immunocytochemistry/ Immunofluorescence

Immunohistochemistry-Paraffin

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: MMP-26

Long Name

Alternate Names

Gene Symbol

Additional MMP-26 Products

Product Documents for MMP26 Antibody

Product Datasheets

COA

Certificate of Analysis

SDS

Product Specific Notices for MMP26 Antibody