MOG Antibody (CL2858)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-46634

Novus Biologicals, part of Bio-Techne
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NBP2-46634
NBP2-46634-25ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry-Frozen

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL2858

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MOG Antibodies »

Product Specifications

Immunogen

Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence ALVGDEVELPCRISPGKNATGMEVGWYRPPFSRVVHLYRNGKDQDGDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKVEDPFYWVSPG

Epitope

GMEVGWYRPP

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for MOG Antibody (CL2858)

Western Blot: MOG Antibody (CL2858) [NBP2-46634]

Western Blot: MOG Antibody (CL2858) [NBP2-46634]

Western Blot: MOG Antibody (CL2858) [NBP2-46634] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10. Lane 2: Human Cerebral Cortex tissue
Immunohistochemistry-Paraffin: MOG Antibody (CL2858) [NBP2-46634]

Immunohistochemistry-Paraffin: MOG Antibody (CL2858) [NBP2-46634]

Immunohistochemistry-Paraffin: MOG Antibody (CL2858) [NBP2-46634] - Staining of human pancreas shows absence of immunoreactivity (negative control).
Immunohistochemistry: MOG Antibody (CL2858) [NBP2-46634]

Immunohistochemistry: MOG Antibody (CL2858) [NBP2-46634]

Immunohistochemistry: MOG Antibody (CL2858) [NBP2-46634] - Staining of rat cerebral cortex shows strong immunoreactivity in myelinated neural fibers.
View 5 more images

Applications for MOG Antibody (CL2858)

Application
Recommended Usage

Immunohistochemistry

1:2500 - 1:5000

Immunohistochemistry-Frozen

Reported in scientific publication (PMID: 32733206)

Immunohistochemistry-Paraffin

1:2500 - 1:5000

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MOG

The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.

Long Name

Myelin Oligodendrocyte Glycoprotein

Alternate Names

MGC26137, MOG Ig-AluB, MOGIG2, myelin oligodendrocyte glycoprotein, myelin-oligodendrocyte glycoprotein

Entrez Gene IDs

4340 (Human)

Gene Symbol

MOG

UniProt

Q16653

Additional MOG Products

Product Documents for MOG Antibody (CL2858)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MOG Antibody (CL2858)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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