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Mouse Angiopoietin-like Protein 2/
ANGPTL2 Antibody

R&D Systems, part of Bio-Techne | Catalog # AF1444

R&D Systems, part of Bio-Techne
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AF1444
AF1444-SP

Key Product Details

Species Reactivity

Validated:

Mouse

Cited:

Mouse

Applications

Validated:

Immunohistochemistry, Western Blot

Cited:

Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Product Specifications

Immunogen

E. coli-derived recombinant mouse Angiopoietin-like 2
Pro23-His493
Accession # Q9R045

Specificity

Detects mouse Angiopoietin-like Protein 2/ANGPTL2 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant mouse (rm) ANGPTL6 and rmANGPTL1 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Mouse Angiopoietin-like Protein 2/ANGPTL2 Antibody

Detection of Mouse Angiopoietin-like Protein 2/ANGPTL2 antibody by Western Blot.

Detection of Mouse Angiopoietin‑like Protein 2/ANGPTL2 by Western Blot.

Western blot shows lysates of mouse uterus tissue and MEF mouse embryonic feeder cells. PVDF membrane was probed with 2 µg/mL of Goat Anti-Mouse Angiopoietin-like Protein 2/ANGPTL2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1444) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band was detected for Angiopoietin-like Protein 2/ANGPTL2 at approximately 60 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Applications for Mouse Angiopoietin-like Protein 2/ANGPTL2 Antibody

Application
Recommended Usage

Immunohistochemistry

5-15 µg/mL
Sample: Immersion fixed frozen sections of mouse embryo (E15), skeletal muscle, and thymus

Western Blot

2 µg/mL
Sample:   Mouse uterus tissue and MEF mouse embryonic feeder cells

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Angiopoietin-like Protein 2/ANGPTL2

Angiopoietinlike2 (ANGPTL2), also known as ANGRP2, is a secreted glycoprotein structurally related to Angiopoietin. It does not bind the Tie1 or Tie2 receptors. ANGPTL2 induces sprouting but is not mitogenic in endothelial cells.

Alternate Names

ANGPTL2, ANGRP2

Entrez Gene IDs

23452 (Human); 26360 (Mouse)

Gene Symbol

ANGPTL2

UniProt

Additional Angiopoietin-like Protein 2/ANGPTL2 Products

Product Documents for Mouse Angiopoietin-like Protein 2/ANGPTL2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Mouse Angiopoietin-like Protein 2/ANGPTL2 Antibody

For research use only

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