Mouse Complement Component C1rLP Antibody
R&D Systems, part of Bio-Techne | Catalog # AF3990
Key Product Details
Species Reactivity
Validated:
Mouse
Cited:
Mouse
Applications
Validated:
Immunoprecipitation, Western Blot
Cited:
Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Goat IgG
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Complement Component C1rLP
Ser18-Asp456
Accession # AAP41417
Ser18-Asp456
Accession # AAP41417
Specificity
Detects mouse Complement Component C1rLP in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 40% cross‑reactivity with recombinant human (rh) C1rLP is observed and less than 1% cross‑reactivity with rhC1R and rhC1S is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for Mouse Complement Component C1rLP Antibody
Application
Recommended Usage
Immunoprecipitation
25 µg/mL
Sample: Conditioned cell culture medium spiked with Recombinant Mouse Complement Component C1rLP, see our available Western blot detection antibodies
Sample: Conditioned cell culture medium spiked with Recombinant Mouse Complement Component C1rLP, see our available Western blot detection antibodies
Western Blot
0.1 µg/mL
Sample: Recombinant Mouse Complement Component C1rLP
Sample: Recombinant Mouse Complement Component C1rLP
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Complement Component C1rLP
Mouse C1rLP, also CLSPa, is a 55 kDa, secreted, atypical glycoprotein member of the AGY group of servine proteases. It has protease activity for pro-haptoglobin, but accomplishes cleavage without a typical Asp in the catalytic site. In addition, it is proposed to block unwanted complement-mediated proteolysis. Mature C1rLP is 443 amino acids (aa) in length. It contains one CUB domain (aa 43‑165), a truncated CCP2 region (aa 167‑223) and a serine protease domain (aa 239‑482). There is a potential short form that utilizes an alternate start site at Met 27. Over aa 44‑456, mouse C1rLP is 78% and 90% aa identical to human and rat C1rLP, respectively.
Long Name
Complement C1r Subcomponent-like Protein
Alternate Names
C1RL, C1RL1, CLSPa
Gene Symbol
C1RL
UniProt
Additional Complement Component C1rLP Products
Product Documents for Mouse Complement Component C1rLP Antibody
Product Specific Notices for Mouse Complement Component C1rLP Antibody
For research use only
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