Mouse DCIR/CLEC4A Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB2617

R&D Systems, part of Bio-Techne
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MAB2617
MAB2617-SP
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Key Product Details

Species Reactivity

Validated:

Mouse

Cited:

Mouse

Applications

Validated:

Western Blot

Cited:

Immunohistochemistry

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2A Clone # 320511

View all DCIR/CLEC4A Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse DCIR/CLEC4A isoform 1
Gln70-Leu238
Accession # Q9QZ15

Specificity

Detects mouse DCIR/CLEC4A in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) DCIR or recombinant mouse DCAR is observed.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Applications for Mouse DCIR/CLEC4A Antibody

Application
Recommended Usage

Western Blot

1 µg/mL
Sample: Recombinant Mouse DCIR/CLEC4A under non-reducing conditions only
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: DCIR/CLEC4A

DCIR (Dendritic Cell Immunoreceptor), also known as LLIR (Lectin-like Immunoreceptor), is a type II membrane protein belonging to the C-type lectin domain family and is designated CLEC4A (previously designated CLECSF6). Four transcript variants encoding distinct isoforms have been identified. DCIR contains one carbohydrate recognition domain in its C-terminal extracellular domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. Besides DC, DCIR is expressed on B cells, monocytes/macrophages and granulocytes.

Long Name

Dendritic Cell Immunoreceptor

Alternate Names

CD367, CLEC4A, CLECSF6, DDB27, LLIR

Entrez Gene IDs

50856 (Human); 26888 (Mouse)

Gene Symbol

CLEC4A

UniProt

Q9QZ15

Additional DCIR/CLEC4A Products

Product Documents for Mouse DCIR/CLEC4A Antibody

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Mouse DCIR/CLEC4A Antibody

For research use only

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