Mouse FAM3B Antibody

R&D Systems, part of Bio-Techne | Catalog # AF2867

R&D Systems, part of Bio-Techne
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AF2867
AF2867-SP
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Key Product Details

Species Reactivity

Validated:

Mouse

Cited:

Human, Mouse

Applications

Validated:

Western Blot

Cited:

Immunocytochemistry, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

View all FAM3B Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse FAM3B
Glu30-Arg235
Accession # Q9D309

Specificity

Detects mouse FAM3B in direct ELISAs and Western blots. In direct ELISAs, approximately 35% cross‑reactivity with recombinant human FAM3B is observed, approximately 5% cross-reactivity with recombinant mouse (rm) FAM3C is observed, and less than 1% cross-reactivity with rmFAM3D is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Mouse FAM3B Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Mouse FAM3B

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
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Qty

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: FAM3B

FAM3B, also known as Pancreatic-Derived factor (PANDER), is a secreted, monomeric, 23 kDa glycoprotein that belongs to a new family of four-helix bundle cytokines. It is highly expressed in pancreatic islet cells and reproductive epithelium. FAM3B has been shown to induce b-cell apoptosis and decrease insulin secretion. Two alternative N-termini, at Glu 30 and Ser 46, have been observed for mature FAM3B. The long version of mature mouse FAM3B shares 80%, 92%, and 75% amino acid sequence homology with the human, rat and canine mature FAM3B, respectively.

Long Name

Family With Sequence Similarity 3, Member B

Alternate Names

PANDER, PRED44

Entrez Gene IDs

54097 (Human)

Gene Symbol

FAM3B

UniProt

Q9D309

Additional FAM3B Products

Product Documents for Mouse FAM3B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Mouse FAM3B Antibody

For research use only

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