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Mouse IL‑16 Antibody

R&D Systems, part of Bio-Techne | Catalog # AF1727

R&D Systems, part of Bio-Techne
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AF1727
AF1727-SP

Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse IL-16
Ser1205-Ser1322
Accession # O54824

Specificity

Detects mouse IL-16 in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant human IL‑16 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Mouse IL‑16 Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Mouse IL-16 C-terminal Peptide

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: IL-16

Interleukin 16, also known as lymphocyte chemoattractant factor (LCF), refers to the C-terminal peptide of mouse pro-IL-16 or neuronal IL-16, which are nuclear and cytoplasmic PD2 domain containing proteins. The C-termini of these proteins are cleaved by Caspase-3, resulting in the release of secreted IL-16. Mature IL-16 has been shown to bind the cell surface receptor CD4 and function as an immunomodulatory cytokine. The C-terminal peptide of human and mouse IL-16 share approximately 86% amino acid sequence identity.

Long Name

Interleukin 16

Alternate Names

IL16, LCF

Entrez Gene IDs

3603 (Human); 16170 (Mouse)

Gene Symbol

IL16

UniProt

Additional IL-16 Products

Product Documents for Mouse IL‑16 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Mouse IL‑16 Antibody

For research use only

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