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Mouse Limitin/IFN- zeta Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB597

R&D Systems, part of Bio-Techne
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MAB597
MAB597-SP

Key Product Details

Species Reactivity

Validated:

Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2A Clone # 183727

Product Summary for Mouse Limitin/IFN- zeta Antibody

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse Limitin/IFN-zeta
Leu22-Arg182
Accession # Q9R1T0

Specificity

Detects mouse Limitin/IFN-zeta in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross‑reactivity with recombinant mouse IFN-gamma is observed.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Applications for Mouse Limitin/IFN- zeta Antibody

Application
Recommended Usage

Western Blot

1 µg/mL
Sample: Recombinant Mouse Limitin (Catalog # 1535-LM)
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Limitin/IFN-zeta

Limitin, also known as IFN-zeta, is a 20 kDa glycoprotein that is secreted by T cells and bronchial and salivary duct epithelial cells. It inhibits B-lineage cell development but has little effect on myelopoiesis or erythropoiesis. Limitin binds to IFN-alpha / beta receptors and has potent antiviral activity. Mouse Limitin shares 32%, 26%, and 30% amino acid sequence identity with mouse IFN-alpha, mouse IFN-beta, and human IFN-omega, respectively.

Long Name

Interferon zeta

Alternate Names

IFN-z, IFNzeta

Entrez Gene IDs

319146 (Mouse)

Gene Symbol

IFNZ

UniProt

Additional Limitin/IFN-zeta Products

Product Documents for Mouse Limitin/IFN- zeta Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Mouse Limitin/IFN- zeta Antibody

For research use only

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