Mouse S100A11 Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB5167
Key Product Details
Species Reactivity
Mouse
Applications
Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Rat IgG2A Clone # 493804
Product Specifications
Immunogen
E. coli-derived recombinant mouse S100A11
Met1-Ile98
Accession # P50543
Met1-Ile98
Accession # P50543
Specificity
Detects mouse S100A11 in direct ELISAs and Western blots. In direct ELISAs, ;no cross-reactivity with recombinant mouse S100A1, 4, 6, 8, 9, 10, 13, or 16 is observed, and approximately 75% cross‑reactivity with recombinant human (rh) S100A11 is observed. In Western blots, no cross‑reactivity with rhS100A11 is observed
Clonality
Monoclonal
Host
Rat
Isotype
IgG2A
Applications for Mouse S100A11 Antibody
Application
Recommended Usage
Western Blot
1 µg/mL
Sample: Recombinant Mouse S100A11
Sample: Recombinant Mouse S100A11
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: S100A11
S100A11, also called calgizzarin or S100C, is an antiproliferative 10 kDa protein that is a member of the S100 family of EF-hand calcium binding proteins. It is found in the cytosol of proliferating fibroblasts and keratinocytes, but in the nucleus in differentiating cells. TGF-beta treatment or calcium-induced S100A11 serine phosphorylation induces nuclear translocation of S100A11 and subsequent growth inhibition in normal cells. The 98 amino acid (aa) mouse S100A11 shares 82% and 94% aa identity with human and rat S100A11, respectively.
Long Name
S100 Calcium Binding Protein A11
Alternate Names
Calgizzarin, MLN70, S100C
Gene Symbol
S100A11
UniProt
Additional S100A11 Products
Product Documents for Mouse S100A11 Antibody
Product Specific Notices for Mouse S100A11 Antibody
For research use only
Loading...
Loading...
Loading...
Loading...