Mouse SCD-1 Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB4404
Key Product Details
Species Reactivity
Validated:
Mouse
Cited:
Mouse
Applications
Validated:
Western Blot
Cited:
Immunohistochemistry
Label
Unconjugated
Antibody Source
Monoclonal Rat IgG2A Clone # 428208
Product Specifications
Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse SCD-1
Met1-Ser355
Accession # P13516
Met1-Ser355
Accession # P13516
Specificity
Detects mouse SCD-1 in direct ELISAs and Western blots.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2A
Applications for Mouse SCD-1 Antibody
Application
Recommended Usage
Western Blot
1 µg/mL
Sample: Recombinant Mouse SCD-1
Sample: Recombinant Mouse SCD-1
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: SCD-1
Stearoyl-CoA Desaturase 1 (SCD-1) is a four-transmembrane endoplasmic reticulum protein that is a rate-limiting enzyme in the formation of triglycerides, cholesteryl esters and phospholipids from saturated fatty acids. Its expression in adipose and liver is enhanced by insulin and certain dietary sugars and fats, and down‑regulated by TNF-alpha. SCD-1 is one of four iron-containing murine stearoyl-CoA desaturases that share 79‑88% aa identity. The 355 aa, predicted 41 kDa mouse SCD-1 shares 92% and 84% aa identity with rat and human SCD-1, respectively.
Long Name
Stearoyl CoA-desaturase 1, Isoform of the Delta9 Desaturase
Alternate Names
SCD1
Gene Symbol
SCD
UniProt
Additional SCD-1 Products
Product Documents for Mouse SCD-1 Antibody
Product Specific Notices for Mouse SCD-1 Antibody
For research use only
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