Mouse TORC1 Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB5978

R&D Systems, part of Bio-Techne
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MAB5978
MAB5978-SP
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Key Product Details

Species Reactivity

Validated:

Mouse

Applications

Immunohistochemistry

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2A Clone # 505531

View all TORC1 Antibodies »

Product Summary for Mouse TORC1 Antibody

Immunogen

E. coli-derived recombinant mouse TORC1
Gln384-Gln471
Accession # Q68ED7

Specificity

Detects mouse TORC1 in direct ELISAs.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Applications for Mouse TORC1 Antibody

Application
Recommended Usage

Immunohistochemistry

8-25 µg/mL
Sample: Perfusion fixed frozen sections of mouse brain (hippocampus)
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 5 using MAB5978 in the following applications:

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
Size / Price
Qty

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: TORC1

TORC1, also known as CREB-regulated transcription coactivator 1 (crtc1), is a 67 kDa member of the TORC family. Mouse TORC1 is 630 amino acids (aa) in length. It contains multiple potential sites for phosphorylation and a serine-rich region from aa 295‑365. Mouse TORC1 is 97% and 90% aa identical to rat and human TORC1, respectively. TORC1 is highly expressed in specific regions of the brain including the cortex, hippocampus, and striatum. It functions as a transcription coactivator for CREB1, which activates transcription through both consensus and variant cAMP response element (CRE) sites.

Long Name

Transducer of Regulated CREB protein 1

Alternate Names

CRTC1, MECT1, WAMTP1

Entrez Gene IDs

23373 (Human); 382056 (Mouse)

Gene Symbol

CRTC1

UniProt

Q68ED7

Additional TORC1 Products

Product Documents for Mouse TORC1 Antibody

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Mouse TORC1 Antibody

For research use only

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