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MPV17 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-52097

Novus Biologicals, part of Bio-Techne
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NBP1-52097

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Canine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Peptide with sequence C-QRALAAHPWKVQ corresponding to internal region according to NP_002428.1.

Epitope

C-QRALAAHPWKVQ

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for MPV17 Antibody

Western Blot: MPV17 Antibody [NBP1-52097]

Western Blot: MPV17 Antibody [NBP1-52097]

Western Blot: MPV17 Antibody [NBP1-52097] - (2ug/ml) staining of Human Frontal Cortex lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for MPV17 Antibody

Application
Recommended Usage

Immunohistochemistry

5 - 10 ug/ml

Peptide ELISA

Detection limit 1:32000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 19 kDa band observed in human brain (frontal cortex) lysates (calculated MW of 19.7 kDa band according to NP_002428.1). An additional band of unknown identity was also consistently observed at 26 kDa. This band was successfully blocked by incubation with the immunizing peptide. IHC-P: Human liver shows heavy textured cystoplasm staining in hepatocytes, consistent with mitochondia.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: MPV17

This gene encodes a mitochondrial inner membrane protein that is implicated in the metabolism of reactive oxygen species. Mutations in this gene have been associated with the hepatocerebral form of mitochondrial DNA depletion syndrome (MDDS).

Alternate Names

human homolog of glomerulosclerosis and nephrotic syndrome, MpV17 mitochondrial inner membrane protein, murine homolog, glomerulosclerosis, protein Mpv17

Entrez Gene IDs

4358 (Human); 17527 (Mouse); 360463 (Rat)

Gene Symbol

MPV17

Additional MPV17 Products

Product Documents for MPV17 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MPV17 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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