MRGX2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00117194-B02P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MRGX2 Antibodies »

Product Specifications

Immunogen

MRGPRX2 (NP_473371.1, 1 a.a. - 330 a.a.) full-length human protein. MDPTTPAWGTESTTVNGNDQALLLLCGKETLIPVFLILFIALVGLVGNGFVLWLLGFRMRRNAFSVYVLSLAGADFLFLCFQIINCLVYLSNFFCSISINFPSFFTTVMTCAYLAGLSMLSTVSTERCLSVLWPIWYRCRRPRHLSAVVCVLLWALSLLLSILEGKFCGFLFSDGDSGWCQTFDFITAAWLIFLFMVLCGSSLALLVRILCGSRGLPLTRLYLTILLTVLVFLLCGLPFGIQWFLILWIWKDSDVLFCHIHPVSVVLSSLNSSANPIIYFFVGSFRKQWRLQQPILKLALQRALQDIAEVDHSEGCFRQGTPEMSRSSLV

Specificity

MRGPRX2,

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Scientific Data Images for MRGX2 Antibody

Western Blot: MRGX2 Antibody [H00117194-B02P]

Western Blot: MRGX2 Antibody [H00117194-B02P]

Western Blot: MRGX2 Antibody [H00117194-B02P] - Analysis of MRGPRX2 expression in transfected 293T cell line by MRGPRX2 polyclonal antibody. Lane 1: MRGPRX2 transfected lysate(36.3 KDa). Lane 2: Non-transfected lysate.
Flow Cytometry: MRGX2 Antibody [H00117194-B02P]

Flow Cytometry: MRGX2 Antibody [H00117194-B02P]

Flow Cytometry: MRGX2 Antibody [H00117194-B02P] - Analysis of negative control 293 cells (Black) and MRGPRX2 expressing 293 cells (Green) using MRGPRX2 purified mouse polyclonal antibody.

Applications for MRGX2 Antibody

Application
Recommended Usage

Flow Cytometry

1:10-1:1000

Western Blot

1:500
Application Notes
This antibody is useful for ELISA, flow cytometry, and Western Blot.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: MRGX2

MRGX2 (MAS-related GPR, member X2) is G-protein coupled 7-transmembrane protein that is selectively expressed in small-diameter sensory neurons of dorsal root ganglia. Human MRGX shares 41-52% amino acid identity with three other primate MRGX proteins, but has no ortholog in rodents. Binding of ligands such as cortistatin, proadrenaomedullin peptides (PAMP-12 and -20) and basic peptides (substance P, neuropeptide Y) to MRGX2 can activate Gq or Gi regulated pathways. MRGX2 is thought to influence nociception and promote adrenal gland catecholamine secretion and IgE-independent mast cell degranulation.

Long Name

Mas-related G Protein-coupled Receptor Member X2

Alternate Names

MRGPRX2

Entrez Gene IDs

117194 (Human)

Gene Symbol

MRGPRX2

UniProt

NP_473371.1 (Human)

Additional MRGX2 Products

Product Documents for MRGX2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for MRGX2 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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