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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # ABCC3/2971

Concentration

0.2 mg/ml

Product Specifications

Immunogen

Recombinant fragment (around aa 815-957) of human MRP3 protein (exact sequence is proprietary) (Uniprot: O15438)

Localization

Cell Surface

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP2-79837)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Scientific Data Images for MRP3 Antibody (ABCC3/2971)

Immunohistochemistry-Paraffin: MRP3 Antibody (ABCC3/2971) [NBP2-79703]

Immunohistochemistry-Paraffin: MRP3 Antibody (ABCC3/2971) [NBP2-79703]

Immunohistochemistry-Paraffin: MRP3 Antibody (ABCC3/2971) [NBP2-79703] - Formalin-fixed, paraffin-embedded human Pancreatic Carcinoma stained with MRP3 Antibody (ABCC3/2971).
Immunohistochemistry-Paraffin: MRP3 Antibody (ABCC3/2971) [NBP2-79703]

Immunohistochemistry-Paraffin: MRP3 Antibody (ABCC3/2971) [NBP2-79703]

Immunohistochemistry-Paraffin: MRP3 Antibody (ABCC3/2971) [NBP2-79703] - Formalin-fixed, paraffin-embedded human Pancreatic Carcinoma stained with MRP3 Antibody (ABCC3/2971).
Immunohistochemistry-Paraffin: MRP3 Antibody (ABCC3/2971) [NBP2-79703]

Immunohistochemistry-Paraffin: MRP3 Antibody (ABCC3/2971) [NBP2-79703]

Immunohistochemistry-Paraffin: MRP3 Antibody (ABCC3/2971) [NBP2-79703] - Formalin-fixed, paraffin-embedded human Pancreatic Carcinoma stained with MRP3 Antibody (ABCC3/2971).

Applications for MRP3 Antibody (ABCC3/2971)

Application
Recommended Usage

Immunohistochemistry

1-2 ug/ml

Immunohistochemistry-Paraffin

1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: MRP3

The protein encoded by the MRP3 gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. (provided by RefSeq)

Long Name

ATP-binding cassette sub-family C member 3

Alternate Names

ABCC3, CMOAT2, EC 7.6.2.3, MLP2, MOAT-D

Gene Symbol

ABCC3

UniProt

Additional MRP3 Products

Product Documents for MRP3 Antibody (ABCC3/2971)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MRP3 Antibody (ABCC3/2971)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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