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MSH2 Antibody (RM478)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-23464

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-23464

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # RM478

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for MSH2 Antibody (RM478)

Immunogen

Recombinant protein within 500 amino acids of the C-terminus of human MSH2 (Uniprot#: P43246)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MSH2 Antibody (RM478)

MSH2 Antibody (RM478)

Western Blot: MSH2 Antibody (RM478) [NBP3-23464] -

Western Blot: MSH2 Antibody (RM478) [NBP3-23464] - Western Blot of HeLa lysate using Clone RM478) at a 1:5000 dilution.
MSH2 Antibody (RM478)

Immunohistochemistry-Paraffin: MSH2 Antibody (RM478) [NBP3-23464] -

Immunohistochemistry-Paraffin: MSH2 Antibody (RM478) [NBP3-23464] - Immunohistochemical staining of formalin fixed and paraffin embedded human colon cancer tissues with MSH2 expression, using Clone RM478) at a 1:100 dilution.
MSH2 Antibody (RM478)

Immunohistochemistry-Paraffin: MSH2 Antibody (RM478) [NBP3-23464] -

Immunohistochemistry-Paraffin: MSH2 Antibody (RM478) [NBP3-23464] - Immunohistochemical staining of formalin fixed and paraffin embedded human tonsil tissue section using Clone RM478) at a 1:100 dilution.

Applications for MSH2 Antibody (RM478)

Application
Recommended Usage

Immunohistochemistry

1:100 -1:200

Western Blot

1:1000 - 1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50% Glycerol/PBS, 1% BSA

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: MSH2

MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC.

Long Name

MutationS Homolog 2

Alternate Names

COCA1, FCC1, HNPCC1, LCFS2

Gene Symbol

MSH2

Additional MSH2 Products

Product Documents for MSH2 Antibody (RM478)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MSH2 Antibody (RM478)

[Public Notes]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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