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MSP/MST1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24996

Novus Biologicals, part of Bio-Techne
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NBP3-24996

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein MSP/MST1 using the following amino acid sequence: PEWYVVPPGTKCEIAGWGETKGTGNDTVLNVALLNVISNQECNIKHRG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MSP/MST1 Antibody

MSP/MST1 Antibody Immunocytochemistry/Immunofluorescence: MSP/MST1 Antibody [NBP3-24996]

Immunocytochemistry/Immunofluorescence: MSP/MST1 Antibody [NBP3-24996]

Staining of human cell line U2OS shows localization to vesicles.

Applications for MSP/MST1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MSP/MST1

Mammalian STE20-like kinase 1, or MST-1, is a serine/threonine kinase that, upon cleavage, has been implicated in the promotion of chromatin condensation. MST-1 is also known as KRS2 and STK4. The C-terminus of MST-1 contains two functional NESs (nuclear export signals), which are released upon caspase-mediated cleavage. The N-terminus portion of the protein then translocates to the nucleus and will promote chromatin condensation at sufficiently high levels. Full-length MST-1 is localized to the cytoplasm.

Long Name

Macrophage Stimulating Protein/Macrophage Stimulating 1 [Hepatocyte Growth Factor-like]

Alternate Names

HGFL, MST1, SF2

Gene Symbol

MST1

Additional MSP/MST1 Products

Product Documents for MSP/MST1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MSP/MST1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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