Key Product Details

Species Reactivity

Human

Applications

Immunoprecipitation, Western Blot (Negative)

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all MST4 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residues 300 and 350 of human Mammalian Ste20-like Kinase 4 (Mst3 and SOK1-related kinase) using the numbering given in entry NP_057626.2 (GeneID 51765).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MST4 Antibody

Immunoprecipitation: MST4 Antibody [NB100-1583]

Immunoprecipitation: MST4 Antibody [NB100-1583]

Immunoprecipitation: MST4 Antibody [NB100-1583] - Detection of Human MST4(MASK) on HeLa whole cell lysate using NB100-1583. Immunoprecipitated MST4(MASK) was blotted using rabbit anti-MST4(MASK) antibody NB100-1584.

Applications for MST4 Antibody

Application
Recommended Usage

Immunoprecipitation

1-4 ug/mg of lysate
Application Notes
For WB use rabbit anti-MST4(MASK) antibody NB 100-1584.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: MST4

MST4/STK24 is a member of the sterile 20 (Ste20)-like kinase family that acts upstream of mitogen-activated protein kinase (MAPK) pathways and regulates c-Jun N-terminal kinase (JNK), p38 and extracellular signal-regulated kinase (ERK). Ste20-like kinases are involved in a variety of cellular processes which include gene transcription, stress responses, cytoskeletal organization and apoptosis. In response to apoptotic signals, MST4/MASK is cleaved by caspase-3 and mediates apoptosis. MST4/MASK has been shown to influence cell growth and transformation by modulating ERK (extracellular signal-regulated kinase) signaling and may play a role in prostrate cancer. MST4/MASK may also play a role in cell motility. Alternate names for MST4/MASK include serine-threonine-protein kinase MST4, STE20-like kinase MST4, MST-4, mammalian STE20-like protein kinase 4, serine/threonine-protein kinase MASK, and mst3 and SOK1-related kinase.

Alternate Names

EC 2.7.11, EC 2.7.11.1, Mammalian STE20-like protein kinase 4, mammalian sterile 20-like 4, MASK, Mst3 and SOK1-related kinase, MST-4, serine/threonine protein kinase MASK, serine/threonine protein kinase MST4, Serine/threonine-protein kinase MASK, serine/threonine-protein kinase MST4, STE20-like kinase MST4

Entrez Gene IDs

51765 (Human)

Gene Symbol

STK26

UniProt

NP_057626.2 (Human)

Additional MST4 Products

Product Documents for MST4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MST4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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