MST4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1584

Novus Biologicals, part of Bio-Techne
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NB100-1584
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Key Product Details

Species Reactivity

Human

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all MST4 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 375 and the C-terminus (residue 416) of human Mammalian Ste20-like Kinase 4 (Mst3 and SOK1-related kinase) using the numbering given in entry NP_057626.2 (GeneID 51765).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MST4 Antibody

Western Blot: MST4 Antibody [NB100-1584]

Western Blot: MST4 Antibody [NB100-1584]

Western Blot: MST4 Antibody [NB100-1584] - Detection of Human MST4(MASK) on HeLa whole cell lysate using NB100-1584. MST4(MASK) was immunoprecipitated using rabbit anti-MST4(MASK) antibody NB100-1583.

Applications for MST4 Antibody

Application
Recommended Usage

Western Blot

1:1000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: MST4

MST4/STK24 is a member of the sterile 20 (Ste20)-like kinase family that acts upstream of mitogen-activated protein kinase (MAPK) pathways and regulates c-Jun N-terminal kinase (JNK), p38 and extracellular signal-regulated kinase (ERK). Ste20-like kinases are involved in a variety of cellular processes which include gene transcription, stress responses, cytoskeletal organization and apoptosis. In response to apoptotic signals, MST4/MASK is cleaved by caspase-3 and mediates apoptosis. MST4/MASK has been shown to influence cell growth and transformation by modulating ERK (extracellular signal-regulated kinase) signaling and may play a role in prostrate cancer. MST4/MASK may also play a role in cell motility. Alternate names for MST4/MASK include serine-threonine-protein kinase MST4, STE20-like kinase MST4, MST-4, mammalian STE20-like protein kinase 4, serine/threonine-protein kinase MASK, and mst3 and SOK1-related kinase.

Alternate Names

EC 2.7.11, EC 2.7.11.1, Mammalian STE20-like protein kinase 4, mammalian sterile 20-like 4, MASK, Mst3 and SOK1-related kinase, MST-4, serine/threonine protein kinase MASK, serine/threonine protein kinase MST4, Serine/threonine-protein kinase MASK, serine/threonine-protein kinase MST4, STE20-like kinase MST4

Entrez Gene IDs

51765 (Human)

Gene Symbol

STK26

UniProt

NP_057626.2 (Human)

Additional MST4 Products

Product Documents for MST4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MST4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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