mtRNA polymerase Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-95264

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP2-95264
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all mtRNA polymerase Antibodies »

Product Specifications

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 42-230 of human POLRMT (NP_005026.3)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for mtRNA polymerase Antibody

Western Blot: mtRNA polymerase Antibody [NBP2-95264]

Western Blot: mtRNA polymerase Antibody [NBP2-95264]

Western Blot: mtRNA polymerase Antibody [NBP2-95264] - Western blot analysis was performed by loading 25 ug of various whole cell lysates probed with Rabbit anti POLRMT (NBP2-95264) at 1:1000 dilution. Arrow points to POLRMT (molecular weight 139 kDa).
Western Blot: mtRNA polymerase Antibody [NBP2-95264]

Western Blot: mtRNA polymerase Antibody [NBP2-95264]

Western Blot: mtRNA polymerase Antibody [NBP2-95264] - Western blot analysis of immunoprecipitate using Rabbit anti POLRMT (NBP2-95264) at 1:1000 dilution. Arrow points to POLRMT (molecular weight 139 kDa).

Applications for mtRNA polymerase Antibody

Application
Recommended Usage

Immunoprecipitation

1:50 - 1:100

Western Blot

1:500 - 1:2000

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

PBS

Preservative

0.05% Proclin 300

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: mtRNA polymerase

POLRMT, also known as DNA-directed RNA polymerase, mitochondrial, is a 246 amino acid protein that is 28 kDa, catalyzes the transcription of mitochondrial DNA into RNA using the four ribonucleoside triphosphates as substrates. This protein is currently being studied for research on autosomal dominant progressive external ophthalmoplegia, essential thrombocythemia, ophthalmoplegia, immunodeficiency, and malaria. This protein has also shown to have interactions with TFB1M, NFKB2, ICT1, TFB2M, TFAM, and over 200 other proteins in ATP/ITP metabolism, mitochondrial gene expression, transcription from mitochondrial promoters, transcription, RNA polymerase I, RNA polymerase III, and mitochondrial transcription, gene expression, and mitochondrial transcription initiation pathways.

Long Name

DNA-directed RNA polymerase, mitochondrial

Alternate Names

EC 2.7.7.6, MtRPOL, POLRMT

Gene Symbol

POLRMT

UniProt

O00411 (Human)

Additional mtRNA polymerase Products

Product Documents for mtRNA polymerase Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for mtRNA polymerase Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.