MUC4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86505

Novus Biologicals, part of Bio-Techne
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NBP1-86505
NBP1-86505-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MUC-4 Antibodies »

Product Summary for MUC4 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: IQYTSNAEDANFTLRDSCTDLELFENGTLLWTPKSLEPFTLEILARSAKIGLASALQPRTVVCHCNAESQCLYNQTSRVGNSSLEVAGCKCDGGTFGRYCEGSEDACEEPCFPSVHCVPGKGCEACPPNLTGD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MUC4 Antibody

Immunohistochemistry-Paraffin: MUC4 Antibody [NBP1-86505]

Immunohistochemistry-Paraffin: MUC4 Antibody [NBP1-86505]

Immunohistochemistry-Paraffin: MUC4 Antibody [NBP1-86505] - Staining of human lung cancer, adenocarcinoma shows moderate cytoplasmic positivity in tumor cells.
Immunohistochemistry-Paraffin: MUC4 Antibody [NBP1-86505]

Immunohistochemistry-Paraffin: MUC4 Antibody [NBP1-86505]

Immunohistochemistry-Paraffin: MUC4 Antibody [NBP1-86505] - Staining of human small intestine shows strong positivity in mucus in goblet cells.
Immunohistochemistry-Paraffin: MUC4 Antibody [NBP1-86505]

Immunohistochemistry-Paraffin: MUC4 Antibody [NBP1-86505]

Immunohistochemistry-Paraffin: MUC4 Antibody [NBP1-86505] - Staining of human colon shows strong cytoplasmic positivity in glandular cells.
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Applications for MUC4 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MUC-4

MUC4 is a constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, and is a highly glycosylated proteins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. MUC4 antibody studies have shown that MUC4 encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. At least two dozen transcript variants of MUC4 have been found, although for many of them the full-length transcript has not been determined or they are found only in tumor tissues. MUC4 is expressed in a wide variety of carcinomas making MUC4 antibodies a key cancer research tool.

Long Name

Mucin 4, Cell Surface-associated

Alternate Names

ASGP, MUC4

Gene Symbol

MUC4

Additional MUC-4 Products

Product Documents for MUC4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MUC4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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