MuRF1/TRIM63 Antibody (M316)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-23424

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # M316

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MuRF1/TRIM63 Antibodies »

Product Summary for MuRF1/TRIM63 Antibody (M316)

Immunogen

Clone M316 was generated from a synthetic peptide (coupled to KLH) corresponding to amino acid residues in the C-terminal half of human MuRF1/TRIM63. This peptide sequence is highly conserved in rat and mouse MuRF1/TRIM63, and has 50% homology to MuRF2 (TRIM-55). [UniProt# Q969Q1]

Specificity

The antibody detects a full length human MuRF1/TRIM63 recombinant protein on SDS-PAGE immunoblots.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

30 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Stable for at least 1 year at -20°C.

Scientific Data Images for MuRF1/TRIM63 Antibody (M316)

MuRF1/TRIM63 Antibody (M316)

Western Blot: MuRF1/TRIM63 Antibody (M316) [NBP3-23424] -

Western Blot: MuRF1/TRIM63 Antibody (M316) [NBP3-23424] - Western blot analysis of human full length MuRF1/TRIM63 recombinant protein. The blot was probed with mouse monoclonal MuRF1/TRIM63 (C-terminal region) at 1:250 (lane 1) and 1:1000 (lane 2) and rabbit polyclonal MuRF1/TRIM63 (C-terminal region) at 1:1000 (lanes 3) and 1:4000 (lane 4).

Applications for MuRF1/TRIM63 Antibody (M316)

Application
Recommended Usage

Western Blot

1:250
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS, 1 mg/ml BSA and 50% glycerol

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C.

Background: MuRF1/TRIM63

MURF1 encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle.

Long Name

Tripartite Motif-containing 63

Alternate Names

IRF, RNF28, SMRZ, TRIM63

Gene Symbol

TRIM63

Additional MuRF1/TRIM63 Products

Product Documents for MuRF1/TRIM63 Antibody (M316)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MuRF1/TRIM63 Antibody (M316)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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