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Muscarinic Acetylcholine Receptor M4/CHRM4 Antibody (18C7.2)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-29705

Novus Biologicals, part of Bio-Techne
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NBP2-29705
NBP2-29705-0.025ml

Key Product Details

Species Reactivity

Human, Rat, Monkey

Applications

Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 18C7.2

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Product Specifications

Immunogen

m4 receptor i3 loop (human), fused to GST.

Specificity

m4 muscarinic acetylcholine receptor. No reactivity with the other subtypes.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

Relevant Entrez Gene Numbers: NM_000741.2

Applications for Muscarinic Acetylcholine Receptor M4/CHRM4 Antibody (18C7.2)

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunoprecipitation

1:10-1:500

Western Blot

1:100-1:2000
Application Notes
Immunohistochemistry (monkey) Western Blot (transfected CHO cell lines) Immunoprecipitation (rat and monkey)

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Ascites with 20mM Phosphate and 0.25M NaCl

Preservative

0.1% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CHRM4

Muscarinic acetylcholine receptor M4 is an Acetylcholine Receptor. Unlike muscarinic receptor M2, the M4 receptor is not involved in smooth muscle contraction. The clinical relevance of this receptor is unknown. However, mouse studies have linked it to adenylyl cyclase inhibition. Muscarinic acetylcholine receptor M4 has been reported to be expressed in many regions of the rat brain, particularly the striatum and hippocampus. ESTs have been isolated from human breast and eye libraries.

Long Name

Cholinergic Receptor Muscarinic 4

Alternate Names

HM4, M4, M4R, mAChR M4

Gene Symbol

CHRM4

UniProt

Additional CHRM4 Products

Product Documents for Muscarinic Acetylcholine Receptor M4/CHRM4 Antibody (18C7.2)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Muscarinic Acetylcholine Receptor M4/CHRM4 Antibody (18C7.2)

Relevant Entrez Gene Numbers: NM_000741.2

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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