Muscarinic Acetylcholine Receptor M4/CHRM4 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS220

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human, Rat, Porcine, Bovine, Equine, Guinea Pig, Hamster

Cited:

Human

Predicted:

Canine (95%), Mouse (100%), Primate (100%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all CHRM4 Antibodies »

Product Specifications

Immunogen

Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human Muscarinic Acetylcholine Receptor M4/CHRM4.

Epitope

3rd cytoplasmic domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%).

Specificity

Human CHRM4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for Muscarinic Acetylcholine Receptor M4/CHRM4 Antibody - BSA Free

Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M4/CHRM4 Antibody - BSA Free [NLS220]

Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M4/CHRM4 Antibody - BSA Free [NLS220]

Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M4/CHRM4 Antibody [NLS220] - Analysis of anti-CHRM4 / M4 antibody with human lymph node, Hodgkins lymphoma.
Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M4/CHRM4 Antibody - BSA Free [NLS220]

Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M4/CHRM4 Antibody - BSA Free [NLS220]

Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M4/CHRM4 Antibody [NLS220] - Analysis of anti-CHRM4 / M4 antibody with human brain, neurons and glia.

Applications for Muscarinic Acetylcholine Receptor M4/CHRM4 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

10 - 20 ug/ml
Application Notes
Use in ICC/IF reported in scientific literature (PMID: 23212463)..

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: CHRM4

Muscarinic acetylcholine receptor M4 is an Acetylcholine Receptor. Unlike muscarinic receptor M2, the M4 receptor is not involved in smooth muscle contraction. The clinical relevance of this receptor is unknown. However, mouse studies have linked it to adenylyl cyclase inhibition. Muscarinic acetylcholine receptor M4 has been reported to be expressed in many regions of the rat brain, particularly the striatum and hippocampus. ESTs have been isolated from human breast and eye libraries.

Long Name

Cholinergic Receptor Muscarinic 4

Alternate Names

HM4, M4, M4R, mAChR M4

Entrez Gene IDs

1132 (Human)

Gene Symbol

CHRM4

UniProt

P08173 (Human)

Additional CHRM4 Products

Product Documents for Muscarinic Acetylcholine Receptor M4/CHRM4 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Muscarinic Acetylcholine Receptor M4/CHRM4 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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