Mxi1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21258

Novus Biologicals, part of Bio-Techne
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NBP3-21258-100ul
NBP3-21258-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Mxi1 Antibodies »

Product Summary for Mxi1 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Mxi1 Antibody

Immunocytochemistry/Immunofluorescence: Mxi1 Antibody [NBP3-21258] -

Immunocytochemistry/Immunofluorescence: Mxi1 Antibody [NBP3-21258] -

Staining of human cell line SH-SY5Y shows localization to nucleoplasm.

Applications for Mxi1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Mxi1

Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.

Long Name

MAX Interacting Protein 1

Alternate Names

MAD2, MXD2, MXI, MXI-WR

Gene Symbol

MXI1

Additional Mxi1 Products

Product Documents for Mxi1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Mxi1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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