Myelin PLP Antibody (CL10622) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-43977

Novus Biologicals, part of Bio-Techne

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human, Rat

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL10622

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all Myelin PLP Antibodies »

Product Specifications

Immunogen

This antibody was generated using a recombinant protein sequence of P60201, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Myelin PLP Antibody (CL10622) - Azide and BSA Free

Myelin PLP Antibody (CL10622) - Azide and BSA Free Immunohistochemistry-Paraffin: Myelin PLP Antibody [NBP3-43977]

Immunohistochemistry-Paraffin: Myelin PLP Antibody [NBP3-43977]

Analysis in human cerebral cortex and tonsil tissues using NBP3-43977 antibody. Corresponding Myelin PLP RNA-seq data are presented for the same tissues.
Myelin PLP Antibody (CL10622) - Azide and BSA Free Immunohistochemistry-Paraffin: Myelin PLP Antibody [NBP3-43977]

Immunohistochemistry-Paraffin: Myelin PLP Antibody [NBP3-43977]

Staining of human cerebellum shows strong positivity in myelinated neuronal processes.
Myelin PLP Antibody (CL10622) - Azide and BSA Free Immunohistochemistry-Paraffin: Myelin PLP Antibody [NBP3-43977]

Immunohistochemistry-Paraffin: Myelin PLP Antibody [NBP3-43977]

Staining of human kidney shows no positivity as expected.
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Applications for Myelin PLP Antibody (CL10622) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Centrifuge the vial of lyophilized antibody at 12,000 x g for 20 seconds. Reconstitute by adding sterile, distilled water to achieve a final antibody concentration of 1mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS with Trehalose

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Myelin PLP

Human PLP (also known as lipophilin) is a 30 kDa protein (277 amino acids) found in myelin of the CNS and PNS. Expressed by oligodendrocytes and Schwann cells, PLP stabilizes myelin by preventing lipid bilayer fusion, and aids in compaction. Different mutations of the human PLP gene product result in two neurological disorders - Pelizaeus-Merzbacher disease and Spastic Paraplegia type 2.

Long Name

Proteolipid Protein

Alternate Names

DM-20, Lipophilin, MMPL, PLP1, SPG2

Gene Symbol

PLP1

Additional Myelin PLP Products

Product Documents for Myelin PLP Antibody (CL10622) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Myelin PLP Antibody (CL10622) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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