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Myelin PLP Antibody (plpc1)

Novus Biologicals, part of Bio-Techne | Catalog # NB600-960

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Bovine

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # plpc1

Concentration

1.0 mg/ml

Product Summary for Myelin PLP Antibody (plpc1)

Immunogen

Synthetic peptide GRGTKF corresponding to C terminal region of myelin proteolipid protein

Specificity

This recognizes myelin proteolipid protein.

Marker

Oligodendrocyte Marker

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for Myelin PLP Antibody (plpc1)

Application
Recommended Usage

Flow Cytometry

1:10-1:1000

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1:100-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

<0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Myelin PLP

Human PLP (also known as lipophilin) is a 30 kDa protein (277 amino acids) found in myelin of the CNS and PNS. Expressed by oligodendrocytes and Schwann cells, PLP stabilizes myelin by preventing lipid bilayer fusion, and aids in compaction. Different mutations of the human PLP gene product result in two neurological disorders - Pelizaeus-Merzbacher disease and Spastic Paraplegia type 2.

Long Name

Proteolipid Protein

Alternate Names

DM-20, Lipophilin, MMPL, PLP1, SPG2

Entrez Gene IDs

281410 (Human)

Gene Symbol

PLP1

UniProt

Additional Myelin PLP Products

Product Documents for Myelin PLP Antibody (plpc1)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Myelin PLP Antibody (plpc1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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