MYO18A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83020

Novus Biologicals, part of Bio-Techne
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NBP1-83020
NBP1-83020-25ul
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human

Predicted:

Mouse (90%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MYO18A Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RFSFSQRSRDESASETSTPSEHSAAPSPQVEVRTLEGQLVQHPGPGIPRPGHRSRAPELVTKKFPVDLRLPPVVPLPPPTLRELELQRRPTGDFGFSLRRTTMLDRGPEGQACRRVVHFAEP

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (89%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MYO18A Antibody

Immunohistochemistry-Paraffin: MYO18A Antibody [NBP1-83020]

Immunohistochemistry-Paraffin: MYO18A Antibody [NBP1-83020]

Immunohistochemistry-Paraffin: MYO18A Antibody [NBP1-83020] - Staining of human cerebral cortex, colon, kidney and skeletal muscle using Anti-MYO18A antibody NBP1-83020 (A) shows similar protein distribution across tissues to independent antibody NBP1-83021 (B).
Immunohistochemistry-Paraffin: MYO18A Antibody [NBP1-83020]

Immunohistochemistry-Paraffin: MYO18A Antibody [NBP1-83020]

Immunohistochemistry-Paraffin: MYO18A Antibody [NBP1-83020] - Staining of human skeletal muscle shows moderate cytoplasmic positivity in myocytes.
Immunohistochemistry-Paraffin: MYO18A Antibody [NBP1-83020]

Immunohistochemistry-Paraffin: MYO18A Antibody [NBP1-83020]

Immunohistochemistry-Paraffin: MYO18A Antibody [NBP1-83020] - Staining of human cerebral cortex shows moderate positivity in neuropil.
View 2 more images

Applications for MYO18A Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MYO18A

Myo18A/Myosin XVIIIA is an unconventional myosin that contains a lysine and glutamine (KE)-rich domain and a PDZ domain. The KE and PDZ domains appear to direct subcellular localization of the Myo18A variants. It is a dimeric actin binding protein that may play a role in the stabilization and organization of the actin cytoskeleton. Recently a cell surface form of Myo18A has been identified as the receptor for surfactant protein A, a lipid-associated lung collectin that mediates innate and adaptive immune responses in the lungs.

Alternate Names

KIAA0216DKFZp686L0243, MAJN, Molecule associated with JAK3 N-terminus, myosin 18A, Myosin containing a PDZ domain, myosin containing PDZ domain, myosin XVIIIA, myosin-XVIIIa, MysPDZ, SP-A receptor subunit SP-R210 alphaS, SPR210

Entrez Gene IDs

399687 (Human)

Gene Symbol

MYO18A

UniProt

Q92614 (Human)

Additional MYO18A Products

Product Documents for MYO18A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MYO18A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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