MYO3A Antibody (8D12)

Novus Biologicals, part of Bio-Techne | Catalog # H00053904-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 8D12

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MYO3A Antibodies »

Product Specifications

Immunogen

MYO3A (NP_059129, 1400 a.a. ~ 1490 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. HEEINNIKKKDNKDSKATSEREACGLAIFSKQISKLSEEYFILQKKLNEMILSQQLKSLYLGVSHHKPINRRVSSQQCLSGVCKGEEPKIL

Reactivity Notes

Human. Other species not tested.

Specificity

MYO3A - myosin IIIA

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Scientific Data Images for MYO3A Antibody (8D12)

Western Blot: MYO3A Antibody (8D12) [H00053904-M01]

Western Blot: MYO3A Antibody (8D12) [H00053904-M01]

Western Blot: MYO3A Antibody (8D12) [H00053904-M01] - MYO3A monoclonal antibody (M01), clone 8D12 Analysis of MYO3A expression in Hela S3 NE.
Sandwich ELISA: MYO3A Antibody (8D12) [H00053904-M01] - Detection limit for recombinant GST tagged MYO3A is approximately 1ng/ml as a capture antibody.

Applications for MYO3A Antibody (8D12)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: MYO3A

The protein encoded by this gene belongs to the myosin superfamily. Myosins are actin-dependent motor proteins and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as this one, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. The protein encoded by this gene plays an important role in hearing in humans. Three different recessive, loss of function mutations in the encoded protein have been shown to cause nonsyndromic progressive hearing loss. Expression of this gene is highly restricted, with the strongest expression in retina and cochlea.

Alternate Names

deafness, autosomal recessive 30, DFNB30, EC 2.7.11, EC 2.7.11.1, myosin IIIA, myosin-IIIa

Entrez Gene IDs

53904 (Human)

Gene Symbol

MYO3A

OMIM

606808 (Human)

UniProt

NP_059129 (Human)

Additional MYO3A Products

Product Documents for MYO3A Antibody (8D12)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MYO3A Antibody (8D12)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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